Project 4: Publications and Presentations

Publications

Agarwal M, Roth K, Yang Z, Sharma R, Maddipati K, Westrick J*, Petriello MC*. Loss of flavin-containing monooxygenase 3 modulates dioxin-like polychlorinated biphenyl 126-induced oxidative stress and hepatotoxicity. Environ Res. 2024 Jun;250:118492. doi:10.1016/j.envres. 2024.118492.

Maxwell A, Swanson G, Nguyen AT, Hu A, Richards D, You Y, Stephan L, Manaloto M, Liao A, Ding J*, Mor G*. Hydroquinone impairs trophoblast migration and invasion via AHR-twist-IFITM1 axis. Placenta. 2024 Sep;155:88-99. doi:10.1016/j.placenta.2024.07.315.

Maxwell DL, Oluwayiose OA, Houle E, Roth K, Nowak K, Sawant S, Paskavitz AL, Liu W, Gurdziel K, Petriello MC*, Richard Pilsner J. Mixtures of per- and polyfluoroalkyl substances (PFAS) alter sperm methylation and long-term reprogramming of offspring liver and fat transcriptome. Environ Int. 2024 Apr;186:108577. doi:10.1016/j.envint.2024.108577.

Agarwal, M., Hoffman, J., Tenlep, S.Y.N., Santarossa, S., Pearson, K.J., Sitarik, A.R., Cassidy-Bushrow, A.E., Petriello, M.C. Maternal polychlorinated biphenyl 126 (PCB 126) exposure modulates offspring gut microbiota irrespective of diet and exercise, in Reproductive Toxicology. 118:108384. doi: 10.1016/j.reprotox.2023.108384. Epub. 2023 Apr 14. PMID: 37061048; PMCID: PMC10257154.

Koshko L, Scofield S, Debarba L, Stilgenbauer L, Sacla M, Fakhoury P, Jayarathne H., Perez-Mojica J.E, Griggs E., Lempradl A., *Sadagurski M. Prenatal benzene exposure alters offspring hypothalamic development predisposing to metabolic disease in later life. Chemosphere, Jul; 330:138738. doi: 10.1016/j.chemosphere. 2023. [PMID: 37084897]

Selected as the NIEHS Superfund Research Program (SRP) Research Brief for Aug 2023

Selected to be featured as an Extramural Paper of the Month in the August edition of the NIEHS Environmental Factor Newsletter

Maxwell, Anthony; Adzibolosu, Nicholas; Hu, Anna; You, Yuan; Stemmer, Paul M; Ruden, Douglas M; Petriello, Michael C; Sadagurski, Marianna; Debarba, Lucas K; Koshko, Lisa. Intrinsic sexual dimorphism in the placenta determines the differential response to benzene exposure. Iscience. 26(4). 2023.

Ruden, Douglas M; Singh, Aditi; Rappolee, Daniel A. Pathological epigenetic events and reversibility review: the intersection between hallmarks of aging and developmental origin of health and disease. Epigenomics. 15(14): 741-754. 2023.

Singh, Aditi; Rappolee, Daniel A; Ruden, Douglas M. Epigenetic Reprogramming in Mice and Humans: From Fertilization to Primordial Germ Cell Development. Cells. 12(14): 1874. 2023.

Ding, Jiahui; Maxwell, Anthony; Adzibolosu, Nicholas; Sadagurski, Marianna; Debarba, Lucas K; Ruden, Douglas M; Petriello, Michael C; Mor, Gil. Benzene Exposure During Pregnancy Leads to Adverse Outcomes in Mice and Significant Transcriptome Changes in Fetal Immune Organs. Reproductive Sciences. 29: 108-109. 2022.

Koshko L, Scofield S, Mor G, *Sadagurski M. Prenatal Pollutant Exposures and Hypothalamic Development: Early Life Disruption of Metabolic Programming. Frontiers in Endocrinology, 11 July 2022 [PMID: 35909533]

Ruden, Douglas M. 10 Years of Toxicogenomics section in Frontiers in Genetics: Past discoveries and Future Perspectives. Frontiers in Genetics. 13: 979761. 2022.

Ruden, Douglas M; Wang, Kai; Wang, Kangxu; Perera, Bambarendage PU; Lee Petroff, Rebekah. Long-term toxicity and epigenetic effects of environmental exposures. Frontiers in Genetics. 13: 1044589. 2022.

Articles Under Review

Debarba LK., Jayarathne HSM, Stilgenbauer L., Terra dos Santos ALR, Koshko L., Scofield S., Sullivan R., Mandal A., Klueh U., Sadagurski M. Microglial NF-κB signaling deficiency protects against metabolic disruptions caused by volatile organic compound via modulating the hypothalamic transcriptome.
https://www.biorxiv.org/content/10.1101/2023.11.08.566279v1